Laser drilling is a proven, economically viable way to create sub-millimeter apertures in pharmaceutical tablets. These apertures play an important role in modern drug delivery systems, which provide many health benefits like decreasing dosing frequencies, achieving consistent drug concentrations in the blood and enabling customized delivery profiles.
Osmotic drug delivery systems are especially valuable, as they control the release of medication into the body. Pharmaceutical tablets for these systems are made in layers—including an indigestible coating, medication, a possible second coating and more medication. Lasers drill through the various layers—creating an aperture or pattern of apertures that release the medication into the stomach. You can meter the medication’s release by varying the size and number of apertures.